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Associated factors with mortality at three‐year follow‐up in a population‐based Mexican elderly cohort study
Author(s) -
Rodríguez Nallely Solano,
Santiago Brenda Margarita Carrillo De,
Ibarrola Mariana Longoria,
AcostaCastillo Gilberto Isaac,
SosaOrtiz Ana Luisa
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.042251
Subject(s) - dementia , medicine , multivariate analysis , cohort , depression (economics) , gerontology , population , cohort study , demography , disease , environmental health , sociology , economics , macroeconomics
Background The highest proportion of deaths occurs in people over 65 years. Factors related to mortality differ between clinical and community population. In Mexico there are few population‐based studies that explore sociodemographic factors, comorbidities, cognitive status and disability, associated with mortality in community elders. Method This is a secondary analysis of the 10/66 Dementia Research Group cohort study, after three years of follow‐up. The participants were evaluated with the protocols of the Dementia Research Group 10/66 Mexico, in 2006 (baseline) and in 2009. We identified two groups deceased and survivors participants and 1,570 participants were selected. Summary and variability measures were calculated, comparing the distribution of both groups. The association of the sociodemographic and clinical variable of interest, with mortality at three years of follow‐up was estimated using multivariate models’ analyses. Result The factors associated with mortality at 3 years of follow‐up were: male gender, being 80 years of age or older, zero education, 3 or less goods or services at home (BSD), presence of dementia, cognitive impairment (CI ), DM ‐2, disability and having suffered 2 or more falls in the last year (table 1). Of the 12 neuropsychiatric symptoms evaluated, only : hallucinations, depression, psychomotor agitation and appetite disturbances, showed significant associations; in the multivariate adjustment the persistent associations were: male gender, dementia, CI and disability (table 2). Conclusion Male gender, the presence of dementia, CI and disability were the factors associated with mortality in Mexican older adults in this analysis. This information contributes to the evidence of relevant factors associated to mortality in Mexican elders. Dementia and CI exceeded the mortality risk of other chronic diseases. In the epidemiological reports , dementia and CI do not appear within the first 10 causes of mortality, probably because they are under‐diagnosed and under‐documented.