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Demographics and survival trends of sinonasal adenocarcinoma from 1973 to 2009
Author(s) -
D'Aguillo Christine M.,
Kanumuri Vivek V.,
Khan Mohemmed N.,
Sanghvi Saurin,
Patel Neal R.,
Baredes Soly,
Eloy Jean Anderson
Publication year - 2014
Publication title -
international forum of allergy and rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.503
H-Index - 46
eISSN - 2042-6984
pISSN - 2042-6976
DOI - 10.1002/alr.21342
Subject(s) - medicine , demographics , epidemiology , demography , retrospective cohort study , cohort , surveillance, epidemiology, and end results , population , race (biology) , cohort study , gerontology , cancer registry , environmental health , botany , sociology , biology
Background The purpose of this work was to study the demographics and survival of patients diagnosed with sinonasal adenocarcinoma (SNAC) within the time period of 1973 to 2009 using the Surveillance, Epidemiology, and End Result (SEER) database. Methods A retrospective cohort study using the U.S. National Cancer Institute's SEER registry was performed to study the demographics and survival for SNAC from 1973 to 2009. Analysis was conducted based on race, gender, and stage. Results In total, 1270 cases of SNAC were analyzed for demographics and survival. Males accounted for 51.6% of cases, while females accounted for 48.4% of cases, amounting to a male to female ratio of 1.06:1.00. Disease specific survival at 5, 10, 15, and 20 years was 65.2%, 50.9%, 40.9%, and 36.5%, respectively. When analyzed by gender, females had higher survival than males, although this difference was not statistically significant. When analyzed by race, the category of other, which encompasses American Indian, Asian, Hispanic, and unknown or unspecified race, was shown to have the best survival, followed by whites and blacks, respectively. Conclusion SNAC is a rare tumor classically associated with occupational exposure and carries a variable prognosis. This is the first dedicated large‐scale, retrospective analysis of a North American SNAC population. SNAC appears to affect both males and females equally and predominantly affects whites. Patients categorized as other had significantly better survival outcomes, while gender appeared to have no significant effect on survival.