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Allergen cross‐reactivity in allergic rhinitis and oral‐allergy syndrome: a bioinformatic protein sequence analysis
Author(s) -
Platt Michael,
Howell Sara,
Sachdeva Ricky,
Dumont Charles
Publication year - 2014
Publication title -
international forum of allergy and rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.503
H-Index - 46
eISSN - 2042-6984
pISSN - 2042-6976
DOI - 10.1002/alr.21340
Subject(s) - epitope , allergen , cross reactivity , allergy , intoxicative inhalant , phylogenetic tree , protein sequencing , medicine , oral allergy syndrome , food allergy , computational biology , biology , immunology , genetics , peptide sequence , gene , antigen , cross reactions , toxicology
Clinical allergy cross-reactivity that is seen with related inhalant allergens or between unrelated inhalant allergens and foods in oral allergy syndrome (OAS) remains poorly understood. The goal of this study is to determine whether clinical cross-reactivity can be identified from primary protein sequences in allergy epitopes and food proteins.