Premium
Impact of intranasal sodium hyaluronate on the short‐term quality of life of patients undergoing functional endoscopic sinus surgery for chronic rhinosinusitis
Author(s) -
Cantone Elena,
Castagna Giovanni,
Sicignano Stefania,
Ferranti Immacolata,
Rega Felice,
Di Rubbo Vittoria,
Iengo Maurizio
Publication year - 2014
Publication title -
international forum of allergy and rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.503
H-Index - 46
eISSN - 2042-6984
pISSN - 2042-6976
DOI - 10.1002/alr.21310
Subject(s) - medicine , functional endoscopic sinus surgery , nasal polyps , sodium hyaluronate , chronic rhinosinusitis , quality of life (healthcare) , sinusitis , nasal administration , saline , surgery , visual analogue scale , endoscopic sinus surgery , anesthesia , immunology , nursing
Background Functional endoscopic sinus surgery (FESS) has become the treatment of choice for patients with medically resistant chronic rhinosinusitis (CRS) and nasal polyps. Despite the consolidated use of different treatments, the postoperative period is often very painful and uncomfortable, especially during the first month. Although evidence on the effectiveness of sodium hyaluronate (SH) on postoperative care following FESS is available, data on the quality of life (QoL) from the patients’ perspective are still lacking. This study aimed to evaluate for the first time the effectiveness of nasal douche with SH in reducing patients’ discomfort during the first month following FESS. Methods A double‐blind randomized controlled study was carried out on 124 subjects undergoing FESS for CRS with nasal polyposis. They were divided into 2 groups: group I was treated with nasal douche containing 9 mg of high molecular weight SH plus saline solution and group II was treated with saline solution alone. To assess QoL in CRS patients, the Short Form‐36 (SF‐36) test, the Sino‐Nasal Outcome Test‐22 (SNOT‐22), and the visual analogue scale (VAS) questionnaires were administered. Results At baseline, there were no statistically significant differences between the 2 groups. However, after 30 days of long postoperative treatments, we found clinically significant improvements in QoL of subjects treated with SH, as evidenced by all QoL scales. Conclusion Our data indicate that SH significantly improves patients’ short‐term QoL following FESS in terms of both general health and specific sinonasal status.