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Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study
Author(s) -
Boyer Holly,
Fernandes Patricia,
Duran Olga,
Hunter David,
Goding George
Publication year - 2011
Publication title -
international forum of allergy and rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.503
H-Index - 46
eISSN - 2042-6984
pISSN - 2042-6976
DOI - 10.1002/alr.20053
Subject(s) - medicine , sclerotherapy , telangiectasia , surgery , perforation , severe bleeding , nose , retrospective cohort study , anesthesia , punching , metallurgy , materials science
Background The aim of this pilot study is to evaluate office‐based sclerotherapy using sodium tetradecyl sulfate (STS) for epistaxis due to hereditary hemorrhagic telangiectasias (HHT). Patients with HHT suffer from unpredictable, recurrent, severe nasal bleeding necessitating emergency care, nasal packing, blood transfusions, and invasive procedures. Methods In this retrospective study 7 patients with a history of treatment for recurrent epistaxis due to HHT were treated in an office‐based setting with intralesional injection of STS. Treatment results were evaluated using a questionnaire. All patients had undergone multiple prior procedures attempting to control epistaxis. Results Patients had an average of 5 sclerotherapy treatments for HHT. Patients were treated using topical and/or local anesthesia with no reports of discomfort. Bleeding requiring intervention did not occur during the procedures. After the procedure all patients (100%) reported significantly less frequent and less severe nasal bleeding. A total of 83% reported that their need for nasal packing was reduced. All patients were willing to undergo the same treatment again. No complications such as perforation, crusting, or foul smell were reported. Conclusion This is the first clinical experience demonstrating that office‐based sclerotherapy with STS is a safe, tolerable, and useful alternative for the treatment of epistaxis due to HHT. © 2011 ARS‐AAOA, LLC.