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Worm Sign: A possible first‐trimester sonographic marker for intracranial haemorrhage resulting in significant cortical disruption
Author(s) -
Elsamadicy Emad,
Kundishora Adam,
Turan Sifa
Publication year - 2021
Publication title -
australasian journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
eISSN - 2205-0140
pISSN - 1836-6864
DOI - 10.1002/ajum.12240
Subject(s) - medicine , sign (mathematics) , first trimester , radiology , intracranial haemorrhage , pregnancy , fetus , neurosurgery , biology , genetics , mathematical analysis , mathematics
Fetal intracranial haemorrhage (ICH) is a pathophysiological process involving haemorrhagic and hypoxic–ischaemic insults resulting in antenatal brain damage. Insults to the central nervous system are usually not detected until the second or third trimester. In this case presentation, we present a possible prenatal ultrasound marker, ‘worm sign’, representing cortical disruption secondary to suspected ICH at 13 weeks’ gestation. According to current literature review, this is one of the first cases of ICH, diagnosed in the first‐trimester and highlights the importance of early neurovascular and structural evaluation of the fetal brain at the time of first‐trimester ultrasound screening.