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Inheritance of digital arches in humans: Is the major gene fully penetrant?
Author(s) -
Chakraborty Ranajit,
Majumder Partha P.,
Mathew Susan,
Satyanarayana M.
Publication year - 1982
Publication title -
american journal of physical anthropology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.146
H-Index - 119
eISSN - 1096-8644
pISSN - 0002-9483
DOI - 10.1002/ajpa.1330580409
Subject(s) - penetrant (biochemical) , inheritance (genetic algorithm) , biology , genetics , gene , computational biology , microbiology and biotechnology
From the fingertip pattern analysis of 125 families with 376 children from Velanadu Brahmin and 100 families with 286 children from Telaganya Brahmin caste sects of Andhra Pradesh, India, the occurrence of an arch on at least one of the ten finger tips is shown to be aggregated in families. The mode of aggregation is in conformity with a major dominant gene with 0.28 chance of penetrance. This is to some extent contradictory to the result published from the analysis of a single Habbanite Jewish pedigree. Some implications of this discordant result are also discussed.