Premium
Segregation distortion at the transferrin locus in Macaca mulatta
Author(s) -
Smith David Glenn
Publication year - 1982
Publication title -
american journal of physical anthropology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.146
H-Index - 119
eISSN - 1096-8644
pISSN - 0002-9483
DOI - 10.1002/ajpa.1330580403
Subject(s) - transferrin , phenotype , allele , locus (genetics) , polyacrylamide gel electrophoresis , electrophoresis , genetics , biology , microbiology and biotechnology , gene , biochemistry , enzyme
The transferrin phenotypes of 256 rhesus monkeys and their parents were identified by polyacrylamide gel electrophoresis. The segregation ratio for phenotypes involving only alleles of high electrophoretic mobility was statistically significantly higher than expected and suggests that selection favors these more negatively charged transferrins. Electrostatic‐dependent processes associated with the binding and transportation of iron might be responsible for this outcome.