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The St. Lawrence Island Eskimos: Genetic variation and genetic distance
Author(s) -
Ferrell Robert E.,
Chakraborty Ranajit,
Gershowitz Henry,
Laughlin W. S.,
Schull W. J.
Publication year - 1981
Publication title -
american journal of physical anthropology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.146
H-Index - 119
eISSN - 1096-8644
pISSN - 0002-9483
DOI - 10.1002/ajpa.1330550309
Subject(s) - genetic variation , purine nucleoside phosphorylase , genetic distance , population , population genetics , biology , geography , evolutionary biology , founder effect , demography , genetics , genotype , haplotype , gene , purine , enzyme , biochemistry , sociology
The Eskimos of St. Lawrence Island have been typed for genetic variation at 44 discrete genetic loci. Three private polymorphisms, at the 2,3‐diphosphoglycerate mutase, peptidase B, and purine nucleoside phosphorylase loci, have been observed, which may be useful in future studies of genetic relationships between Eskimos and other circumpolar populations. Genetic distance analysis reveals a close relationship between the St. Lawrence Island Eskimos and other Eskimo populations and that the Eskimo populations form a distinct cluster from Amerindian populations. The St. Lawrence Island Eskimos appear to be more similar to Asiatic Eskimos than to other groups. Caucasian admixture in this population is estimated to be between 2 and 7%.