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Restriction and persistence of polymorphisms of HLA and other blood genetic traits in the Parakanã Indians of Brazil
Author(s) -
Black Francis L.,
Salzano Francisco M.,
Layrisse Zulay,
Franco M. Helena L. P.,
Harris Nancy S.,
Weimer Tania A.
Publication year - 1980
Publication title -
american journal of physical anthropology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.146
H-Index - 119
eISSN - 1096-8644
pISSN - 0002-9483
DOI - 10.1002/ajpa.1330520115
Subject(s) - allele , persistence (discontinuity) , genetics , biology , human leukocyte antigen , tribe , evolutionary biology , gene , antigen , sociology , geotechnical engineering , anthropology , engineering
Results concerning HLA types and 22 other blood genetic systems are reported for the Parakanã Indians of northern Brazil, a tribe that is notable for the light color and pilosity of some of its members. No clear evidence of Caucasoid admixture was found, but the Parkanã show unusual frequencies in the EsD 1 , PGM 1 1 , Gc 2 , Cp B , Fy a , Di a , and L M genetic markers. In addition, the very rare Rh allele r y is present, as well as what seems to be a new PGM 2 variant. There is very limited heterogeneity in the HLA system. All these distinctive features may have arisen through a combination of founder effects and genetic drift. However, low F is values, as well as higher mean ages in heterozygous as compared to homozygous persons, suggest that an heterotic effect is counteracting these dispersive forces.