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Immunoglobulin (Gm) allotypes in a sample of Canadian Ashkenazic jews
Author(s) -
Field L. Leigh,
Lowden J. Alexander,
Ray Ajit K.
Publication year - 1978
Publication title -
american journal of physical anthropology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.146
H-Index - 119
eISSN - 1096-8644
pISSN - 0002-9483
DOI - 10.1002/ajpa.1330480206
Subject(s) - sample (material) , antibody , genetics , biology , chemistry , chromatography
Gm typing on the serum specimens of 507 Ashkenazic Jews (predominantly of Polish‐Russian ancestry) from Toronto, Canada has established the presence of haplotypes Gm 3;5 , Gm 1;21 , Gm 1,2;21 , and Gm 1,17;5 , and the absence of haplotypes Gm 1;13,15,16 , Gm 1;5,6 , and Gm 1;5,6,24 which have been found in other Jewish peoples. It is suggested that Ashkenazic populations have lower frequencies of haplotype Gm 1,17;5 than non‐European Jewish populations, and that some eastern European Jewish populations have acquired the Gm 1;13,15,16 haplotype through gene flow from Central Asia. Thus Jewish populations show differences in the Gm system; many of the differences may be in the direction of similarities to neighbouring non‐Jewish populations.