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Genetic differentiation among Sardinian villages
Author(s) -
Workman P. L.,
Lucarelli P.,
Agostino R.,
Scarabino R.,
Scacchi R.,
Carapella E.,
Palmarino R.,
Bottini E.
Publication year - 1975
Publication title -
american journal of physical anthropology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.146
H-Index - 119
eISSN - 1096-8644
pISSN - 0002-9483
DOI - 10.1002/ajpa.1330430204
Subject(s) - evolutionary biology , biology , geography , genetics , genealogy , history
The present study reports an analysis of genetic differentiation among 14 Sardinian villages located mainly in the center of the island. Chisquare tests show significant genetic heterogeneity among villages, and analyses by F‐ and R‐ statistics indicate an essentially random pattern of differentiation for all alleles. Using the kinship methods of Morton, a matrix, R, with elements r ij describing the correlations between the gene frequencies of villages i and j is obtained. Use of Malécot's formula relating the r ij to the geographic distances between villages shows a rapid decline of kinship with increasing distance but reveals essentially no relationship for distances over 40 km. Rotation of a two‐dimensional reduction of the kinship matrix to maximum congruence with the geographic distances indicates that about 25% of the genetic distances can be accounted for by the geographic location of the villages. Isolation due in part to cultural factors, genetic drift, and special local or regional patterns of villages associations appear to be involved in the pattern of genetic variation.