Premium
Considering human–primate transmission of measles virus through the prism of risk analysis
Author(s) -
JonesEngel Lisa,
Engel Gregory A.,
Schillaci Michael A.,
Lee Benjamin,
Heidrich John,
Chalise Mukesh,
Kyes Randall C.
Publication year - 2006
Publication title -
american journal of primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 81
eISSN - 1098-2345
pISSN - 0275-2565
DOI - 10.1002/ajp.20294
Subject(s) - virology , measles virus , prism , measles , transmission (telecommunications) , primate , non human primate , biology , computer science , evolutionary biology , vaccination , neuroscience , telecommunications , optics , physics
Measles is a respiratory virus that is endemic to humans. Human–nonhuman primate (NHP) transmission of the measles virus has been shown to cause significant morbidity and mortality in NHP populations. We investigated serological evidence of exposure to measles virus in two free‐ranging populations of macaques at the Bukit Timah (BTNR) and Central Catchment Nature (CCNR) reserves in Singapore and the Swoyambhu Temple in Katmandu, Nepal. At BTNR/CCNR none of the 38 macaques ( Macaca fascicularis ) sampled were seropositive for antibodies to measles virus. In contrast, at Swoyambhu 100% (n=39) of the macaques ( M. mulatta ) sampled were seropositive for antibodies to the measles virus. Here the contrasting seroprevalences of the two sites are analyzed using risk analysis. These case studies show how risk analysis can be used to approach the phenomenon of cross‐species pathogen transmission. Am. J. Primatol. 68:868–879, 2006. © 2006 Wiley‐Liss, Inc.