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Identification of Helicobacter sp. in gastric mucosa from captive marmosets ( Callithrix sp.; callitrichidae, primates)
Author(s) -
de Mello Marcela Freire Vallim,
Monteiro Ana Beatriz Soares,
Fonseca Eliene Carvalho,
Pissinatti Alcides,
Ferreira Ana Maria Reis
Publication year - 2005
Publication title -
american journal of primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 81
eISSN - 1098-2345
pISSN - 0275-2565
DOI - 10.1002/ajp.20131
Subject(s) - callithrix , marmoset , biology , helicobacter , immunohistochemistry , helicobacter pylori , gastric mucosa , pathology , h&e stain , stomach , immunology , medicine , paleontology , biochemistry , genetics
The aim of this study was to identify the presence of Helicobacter sp. in the gastric mucosa of captive marmosets ( Callithrix sp.). Histologic specimens from the fundic, corpus, and antral gastric regions of six Callithrix jacchus , 12 C. kuhli , and 12 C. geoffroyi specimens were evaluated. The sections were stained with hematoxylin‐eosin (H&E) and the Warthin‐Starry silver impregnation method, and immunostained with rabbit anti‐ H. pylori polyclonal antibody. Helicobacter ‐like organisms (HLOs) and coccoid forms were present in silver‐stained sections from 29 stomachs, whereas immunohistochemistry (IHC) tests revealed bacterial aggregates in 15 stomachs. No statistical difference relative to the presence of Helicobacter sp. was found among the gastric regions or marmoset species. Gastric lesions were found in the groups of marmosets that had positive and negative IHC results, but no correlation between inflammation and Helicobacter sp. infection was established. These findings demonstrate that marmosets are susceptible to naturally‐occurring Helicobacter sp. infection, and open the way to the development of comparative studies on Helicobacter sp. infection in humans. Am. J. Primatol. 66:111–118, 2005. © 2005 Wiley‐Liss, Inc.