Premium
Renal clearance and excretion of endogenous substances in the owl monkey
Author(s) -
Weller Richard E.,
Baer Janet F.,
Málaga Carlos A.,
Buschbom Raymond L.,
Ragan Harvey A.
Publication year - 1992
Publication title -
american journal of primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 81
eISSN - 1098-2345
pISSN - 0275-2565
DOI - 10.1002/ajp.1350280204
Subject(s) - renal function , urinalysis , excretion , creatinine , medicine , endocrinology , urinary system , urine , fractional excretion of sodium , potassium , chemistry , kidney , electrolyte , sodium , renal physiology , organic chemistry , electrode
The clearance and excretion of creatinine, calcium, phosphorus, sodium, and potassium by the kidney was evaluated in 62 owl monkeys using timed urine collections and quantitative urinalyses. The endogenous clearance of creatinine was determined for each monkey. Urinary electrolyte excretion and fractional electrolyte excretions (FE) were measured. Linear regression analysis was used to calculate the correlation between urinary excretion and FE for each electrolyte. The coefficient of determination for each analyte was significant (P ⩽ .0001). Determination of FE was found to be an appropriate indicator of the renal handling of electrolytes and, when viewed in conjunction with urinalysis and other serum parameters, an aid in evaluating renal function in the owl monkey. © 1992 Wiley‐Liss, Inc.