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Cerebral palsy in a macaque monkey
Author(s) -
Fitch H.,
Coen R.,
Lindburg D.,
Robinson P.,
Hajek P.,
Hesselink J.,
Crutchfield S.
Publication year - 1988
Publication title -
american journal of primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 81
eISSN - 1098-2345
pISSN - 0275-2565
DOI - 10.1002/ajp.1350140209
Subject(s) - cerebral palsy , macaque , magnetic resonance imaging , medicine , nystagmus , cerebral infarction , rhesus macaque , pediatrics , psychology , audiology , physical medicine and rehabilitation , neuroscience , ischemia , radiology , immunology
Magnetic resonance imaging was used to document brain lesions symptomatic of cerebral palsy in the macaque monkey exhibiting poor motor control and periodic episodes of ocular nystagmus and convulsive twitching. Neuroanatomic deficits most likely resulted from hemorrhage or ischemic infarction at or near the time of birth. Extreme maternal dependency and retarded behavioral development were documented at 3 and 12 months of age. Both social and motor behavior improved significantly when observed at 30 months of age after therapy.