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Serum concentrations of 1,25‐dihydroxyvitamin D 3 in Platyrrhini and Catarrhini: A phylogenetic appraisal
Author(s) -
Adams John S.,
Gacad Mercedes A.,
Baker Andrew J.,
Gonzales Benjamin,
Rude Robert K.
Publication year - 1985
Publication title -
american journal of primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 81
eISSN - 1098-2345
pISSN - 0275-2565
DOI - 10.1002/ajp.1350090307
Subject(s) - biology , vitamin d and neurology , endocrinology , medicine
Abstract We measured the serum concentration of 25‐hydroxyvitamin D 3 (25‐OH‐D 3 ) and 1,25‐dihydroxyvitamin D 3 (1,25‐[OH] 2 ‐D 3 ) in 23 different Platyrrhines from four different genera and in 21 Catarrhines from six different genera in residence at the Los Angeles Zoo. The mean (±S.E.) serum concentration of 1,25‐(OH) 2 ‐D 3 was significantly greater in Platyrrhines (810 ± 119 pg/ml) than in Catarrhines (61 ± 5 pg/ml), suggesting that high circulating concentrations of the active vitamin D hormone were a characteristic of New World primates in both the Cebidae and Callitrichidae family. This increase in the serum concentration of 1,25‐(OH) 2 ‐D 3 is probably an adaptational response on the part of Platyrrhini to offset a relative decrease in the concentration of specific receptor for 1,25‐(OH) 2 ‐D 3 in target tissues for the hormone.