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Synthetic Approaches of Prelactone and Its Analogues: A Review
Author(s) -
Tadiparthi Krishnaji,
Devaroy Monisha J. L.,
Panigrahi Amrita,
Sakirolla Raghavendra
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202100320
Subject(s) - chemistry , enantioselective synthesis , epimer , combinatorial chemistry , nanotechnology , stereochemistry , organic chemistry , catalysis , materials science
In this review we have discussed the synthetic approaches of prelactones and their epimers from 1997 to date. The presence of unique molecular architecture and its high biological importance enhanced the research activity over the last two decades. Most of the syntheses involve either a chiral auxiliary, chiral pool or catalytic enantioselective approaches as a key step. Overall this review highlights the contribution from different research groups in the total synthesis of various prelactones.