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Organophotoredox‐Catalyzed Late‐Stage Functionalization of Heterocycles
Author(s) -
Kumar Hota Sudhir,
Jinan Dilsha,
Prakash Panda Satya,
Pan Rittwika,
Sahoo Basudev,
Murarka Sandip
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202100234
Subject(s) - photoredox catalysis , surface modification , chemistry , catalysis , combinatorial chemistry , organic synthesis , nanotechnology , organic chemistry , photocatalysis , materials science
In the last decade, visible light photoredox catalysis promoting radical‐based organic transformations has received enormous synthetic applicability, as they allow unfolding of site‐selective reactivities under mild reaction conditions. Moreover, the photoredox transformations utilizing organic dyes as photocatalysts are attractive with regard to low cost, less toxicity, easy availability and high functional group tolerance. The organophotoredox‐catalyzed reaction technologies enabling direct, efficient and selective late‐stage functionalization of various heterocycles leading to the formation of various C−C and C−X (X=N, P, O, S, Se, Br) bonds have emerged at the forefront of synthetic methodologies available to synthetic chemists. This minireview summarizes the developments made in the last five years in the field of late‐stage functionalization of heterocycles governed by various organophotocatalysts and intends to provide the readers a comprehensive overview of this research field with representative examples and mechanistic insights.