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Gold‐Catalyzed Tandem Cycloisomerization/Ring Expansion of Alkynyl Spiro‐epoxyoxindoles: Access to Furo[2,3‐c]quinolinone Derivatives
Author(s) -
Xiao JunAn,
Peng Hai,
Liang JinShao,
Luo XiaoYan,
Cheng XiuLiang,
Su Wei
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202100202
Subject(s) - cycloisomerization , chemistry , tandem , ring (chemistry) , catalysis , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry , materials science , composite material
A gold‐catalyzed tandem cycloisomerization/ring expansion of alkynyl spiro‐epoxyoxindoles was developed, affording furo[2,3‐c]quinolinones in good to excellent yields with broad substrates scope. This methodology provides an efficient approach to construct furo[2,3‐c]quinolinone moieties. Moreover, the fluorescence properties of furo[2,3‐c]quinolinones are also investigated.