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Rhodium‐Catalyzed O−H Bond Insertion Reaction between H‐Phosphoryl Compounds and 2‐Pyridyl Carbenes Generated from Pyridotriazoles
Author(s) -
Dong Chao,
Zhang Can,
Wang Xin,
Shen Ruwei
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202100195
Subject(s) - chemistry , rhodium , catalysis , reactivity (psychology) , diazo , insertion reaction , medicinal chemistry , selectivity , metal , stereochemistry , organic chemistry , medicine , alternative medicine , pathology
The dirhodium(II) tetraacetate‐catalyzed O−H bond insertion reaction between H‐phosphoryl compounds and 2‐pyridyl carbenes generated from pyridotriazoles is reported to afford a new synthesis of 2‐picolyl phosphinates and phosphates in good to high yields with high selectivity. This new reaction represents a rare example showing a unique reactivity of the P(O)−H ( vs PO−H) functionality of H‐phosphoryl compounds with respect to the insertion reactions of diazo compounds under transition metal catalysis.