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Development of a Liquid‐Liquid Biphasic Reaction Using a Taylor Vortex Flow Reactor
Author(s) -
Hosoya Masahiro,
Manaka Atsushi,
Nishijima Shogo,
Tsuno Naoki
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202100166
Subject(s) - slug flow , chemistry , vortex , flow (mathematics) , volumetric flow rate , flow chemistry , mechanics , liquid flow , tube (container) , slug , reaction rate , thermodynamics , catalysis , two phase flow , materials science , organic chemistry , physics , composite material , cancer research , biology
This paper describes a liquid‐liquid biphasic flow reaction system that is simple to control. In a liquid‐liquid biphasic flow reaction, the slug‐flow in the tube reactors generally improves the reaction rate. However, we show that larger tube diameters decreased the reaction rate and the formation of the slug‐flow was influenced by the tube diameter, the size of the mixer, and the pump mechanism. These results indicated that technical difficulties with the slug‐flow could be an obstacle to scale‐up. To resolve this problem, we suggest the use of a Taylor vortex flow reactor to achieve a higher reaction rate than with batch and slug‐flow systems.