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Indium‐Catalyzed Deoxygenation of Sulfoxides with Hydrosilanes
Author(s) -
Sakai Norio,
Shimada Retsu,
Ogiwara Yohei
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202100063
Subject(s) - deoxygenation , chemistry , catalysis , sulfide , indium , reactivity (psychology) , sulfoxide , organic chemistry , sulfur , combinatorial chemistry , medicine , alternative medicine , pathology
Described herein is that a novel InBr 3 /PhSiH 3 reducing system in a 1,4‐dioxane solution smoothly and effectively undertook deoxygenation of a variety of sulfoxides leading to the facile preparation of sulfide derivatives. Also, it was demonstrated that the reducing system shows a higher reactivity towards sulfoxides than that towards commonly reducible functional groups, such as carboxylic acids, esters, amides, and sulfones.