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AIBN‐Initiated Oxidative Deoximation Reaction: A Metal‐Free and Environmentally‐Friendly Protocol
Author(s) -
Wang Feng,
Chen Tian,
Shi Yaocheng,
Yu Lei
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202000675
Subject(s) - chemistry , environmentally friendly , molecular oxygen , oxidative phosphorylation , reaction conditions , radical initiator , redox , transition metal , oxygen , combinatorial chemistry , organic chemistry , catalysis , biochemistry , polymerization , ecology , polymer , biology
Abstract AIBN, a very common free radical initiator, was found to be efficient for oxidative deoximation reactions. The process could employ molecular oxygen as the mild, clean and safe oxidant in most cases and did not involve any transition metals. The applied initiator loading was as low as 2 mol%. This work reports a relatively green method for deoximation reactions and may be very practical for large‐scale applications.