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Copper‐Catalyzed Decarboxylative Reductive Sulfonylation of α‐Oxocarboxylic Acids with Aryl Sulfonyl Hydrazines
Author(s) -
Wu Zhiyong,
Hao Shuai,
Hu Jingyan,
Shen Hongtao,
Lai Miao,
Liu Pengfei,
Xi Gaolei,
Wang Pengfei,
Zhao Shengchen,
Zhang Xiaoping,
Zhao Mingqin
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202000583
Subject(s) - chemistry , aryl , sulfonyl , catalysis , decarboxylation , organic chemistry , combinatorial chemistry , sulfone , copper , alkyl
A novel and facile synthesis of aryl benzyl sulfones was accomplished for the first time through copper‐catalyzed decarboxylative reductive sulfonylation reaction between α‐oxocarboxylic acids and aryl sulfonyl hydrazines. The protocol proceeds smoothly under simple conditions, and has the advantages of simple operation, high yields and good functional group compatibility. This approach realizes a conceptually novel methodology for aryl benzyl sulfone synthesis under a decarboxylative reductive progress.