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Recent Advances in Reductive Desymmetrization of Diketones
Author(s) -
Ding YiXuan,
Zhu ZhouHao,
Yu ChangBin,
Zhou YongGui
Publication year - 2020
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202000536
Subject(s) - desymmetrization , chemistry , homogeneous , ketone , combinatorial chemistry , organic chemistry , enantioselective synthesis , catalysis , physics , thermodynamics
Reductive desymmetrization of achiral or meso diketones has attracted considerable attention due to these motifs which play important roles in organic synthesis, pharmaceuticals and functional materials. This review focuses on recent advances in homogeneous reductive desymmetrization of 1,2‐, 1,3‐ and 1,4‐diketones, which provides an efficient and practical access to structurally diverse chiral α‐, β‐ or γ‐hydroxy ketone derivatives.