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Copper‐Catalyzed Direct Oxidative Aroylations of Quinoxalinones with Methylarenes
Author(s) -
Clinton Chayan Dhar,
Prasad Ch. Durga,
Khanal Hari Datta,
Lee Yong Rok
Publication year - 2021
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202000523
Subject(s) - chemistry , oxidative phosphorylation , catalysis , copper , combinatorial chemistry , functional group , organic chemistry , biochemistry , polymer
An efficient methodology for the copper‐catalyzed direct oxidative aroylations of quinoxalin‐2(1 H )‐ones with methylarenes is reported. This methodology offers an efficient access to diverse and polyfunctionalized 3‐aroylated quinoxalin‐2(1 H )‐ones starting from readily available quinoxalin‐2(1 H )‐ones and various methylarenes using TBHP as an oxidant. This protocol is broadly compatible with diverse substrates and is highly functional‐group tolerant.