Premium
Base‐Promoted Regiospecific Synthesis of Fully Substituted 1,2,3‐Triazoles and 1,5‐Disubstituted 1,2,3‐Triazoles
Author(s) -
Zhang Xueying,
Cui Xue,
Wang Wei,
Zeng Tingting,
Wang Yan,
Tan Yinfeng,
Liu Dongyan,
Wang Xuesong,
Li Youbin
Publication year - 2020
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202000479
Subject(s) - chemistry , diazo , cleavage (geology) , combinatorial chemistry , bond cleavage , stereochemistry , substrate (aquarium) , medicinal chemistry , catalysis , organic chemistry , oceanography , geotechnical engineering , fracture (geology) , engineering , geology
An efficient strategy have been developed for the synthesis of fully substituted 1,2,3‐triazoles and 1,5‐disubstituted 1,2,3‐triazoles subsequently by C−C bond cleavage. Regitz diazo‐transfer and C−C bond cleavage process were involved in this reaction to give 1,2,3‐triazoles with good substrate tolerance. This protocol provideed a facile and an expeditious approach for the assembly of diversely structural 1,2,3‐triazoles.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom