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Rhodium‐Catalyzed Selective C−H Bond Functionalization of Quinolines
Author(s) -
Dhiman Ankit K.,
Thakur Ankita,
Kumar Rakesh,
Sharma Upendra
Publication year - 2020
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202000341
Subject(s) - rhodium , chemistry , surface modification , quinoline , catalysis , iridium , palladium , combinatorial chemistry , ruthenium , selectivity , organic chemistry
In the last two decades, rhodium‐based catalysts have been used extensively for the sp 2 and sp 3 C−H bond activation/functionalization of various arenes, heteroarenes, and aliphatic compounds, respectively. For quinoline functionalization rhodium has been used significantly as compared to other transition metals such as cobalt, copper, ruthenium, palladium and iridium. In this Minireview the progress on rhodium‐catalyzed selective functionalization of quinoline N ‐oxides and 8‐methylquinolines via sp 2 and sp 3 C−H bond activation, respectively have been highlighted. The main focus is on reaction mechanism, substrate scope, and positional selectivity.