Premium
Iridium‐Catalyzed α‐Alkylation of Arylacetonitriles Using Secondary and Primary Alcohols
Author(s) -
Kong YingYing,
Wang ZhongXia
Publication year - 2020
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202000244
Subject(s) - chemistry , alkylation , primary (astronomy) , catalysis , yield (engineering) , iridium , organic chemistry , combinatorial chemistry , physics , astronomy , materials science , metallurgy
In the presence of NaO t Bu, [Cp*IrCl 2 ] 2 ‐catalyzed reaction of arylacetonitriles with secondary alcohols was performed to yield α‐monoalkylation products of arylacetonitriles. The catalyst and conditions also suited for the α‐monoalkylation of arylacetonitriles with primary alcohols.