Indazolone‐Assisted Sequential  ortho ‐Alkenylation‐Oxidative Aza‐Michael Addition of 1‐Arylindazolone Using Acrylates Under Ru(II) Catalysis | Zendy

Mahesha Chikkagundagal K. | Zendy; Mandal Sanjay K. | Zendy; Sakhuja Rajeev | Zendy

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Indazolone‐Assisted Sequential ortho ‐Alkenylation‐Oxidative Aza‐Michael Addition of 1‐Arylindazolone Using Acrylates Under Ru(II) Catalysis

Author(s) -

Mahesha Chikkagundagal K.,

Mandal Sanjay K.,

Sakhuja Rajeev

Publication year - 2020

Publication title -

asian journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 44

eISSN - 2193-5815

pISSN - 2193-5807

DOI - 10.1002/ajoc.202000239

Subject(s) - chemistry , intramolecular force , moiety , catalysis , oxidative phosphorylation , michael reaction , functional group , annulation , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , biochemistry , polymer

A one‐pot annulation of 1‐arylindazolones and acrylates is achieved through Ru(II)‐catalyzed sequential ortho ‐alkenylation followed by oxidative intramolecular aza‐Michael addition reaction to deliver substituted indazolo[1,2‐ a ]indazolylidenes in good‐to‐excellent yields. The strategy showcased high functional group tolerance and the directing group ability of indazolone moiety was established for Csp 2 ‐H bond activation.

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