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Direct Access to (±)‐10‐Desbromoarborescidine A from Tryptamine and Pentane‐1,5‐diol
Author(s) -
Sahoo Apurba Ranjan,
Lalitha Gummidi,
Murugesh V.,
Bruneau Christian,
Sharma Gangavaram V. M.,
Suresh Surisetti,
Achard Mathieu
Publication year - 2020
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.202000188
Subject(s) - tryptamine , pentane , phosphine , ruthenium , chemistry , diol , ligand (biochemistry) , combinatorial chemistry , condensation , stereochemistry , catalysis , organic chemistry , biochemistry , receptor , physics , thermodynamics
A single step synthetic strategy for (±)10‐ desbromoarborescidine A is described. Starting from tryptamine and pentane‐1,5‐diol, this acceptorless dehydrogenative condensation process is efficiently catalyzed by a ruthenium complex featuring proton‐responsive phosphine‐pyridone ligand.

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