Premium
Transition‐Metal‐Free Approaches to Arylsulfones using Benzylic Ammonium Salts through C−N Bond Cleavage
Author(s) -
Liu Yishuai,
Zhu Haibo,
Yang Liu,
Xie Zongbo,
Jiang Guofang,
Le ZhangGao,
Tu Tao
Publication year - 2020
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900759
Subject(s) - chemistry , ammonium , bond cleavage , transition metal , cleavage (geology) , sodium , metal , organic chemistry , combinatorial chemistry , catalysis , geotechnical engineering , fracture (geology) , engineering
A transition‐metal‐free approach to benzyl sulfones by using sodium sulfinates and benzyl ammonium salts is described. The protocol provides a simple and direct method to realize the C−N bond cleavage in the presence of readily available Cs 2 CO 3 . During the reaction process, a range of functional groups with respect to both sodium sulfinates and benzylic ammonium salts were well compatible, leading to various benzyl sulfones in moderate to good yields.