A Free Radical Cascade Difunctionalization of  o ‐Vinylanilides with Simple Ketones and Esters | Zendy

Tian Yunfei | Zendy; Ge Yaxin | Zendy; Zheng Luping | Zendy; Yan Qinqin | Zendy; Ren Yingming | Zendy; Wang Zhenguang | Zendy; Zhang Kailin | Zendy; Wang Zhiqiang | Zendy; Zhao Jincan | Zendy; Li Zejiang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A Free Radical Cascade Difunctionalization of o ‐Vinylanilides with Simple Ketones and Esters

Author(s) -

Tian Yunfei,

Ge Yaxin,

Zheng Luping,

Yan Qinqin,

Ren Yingming,

Wang Zhenguang,

Zhang Kailin,

Wang Zhiqiang,

Zhao Jincan,

Li Zejiang

Publication year - 2019

Publication title -

asian journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 44

eISSN - 2193-5815

pISSN - 2193-5807

DOI - 10.1002/ajoc.201900591

Subject(s) - chemistry , cascade , radical cyclization , cascade reaction , combinatorial chemistry , free radical reaction , organic chemistry , radical , catalysis , chromatography

An efficient free radical cascade difunctionalization of o ‐vinylanilides with ketones/esters has been developed. Through the selective activation of the α‐C(sp 3 )−H of ketones and esters, an addition/cyclization of carbon centered radical to o‐vinylanilides has been achieved. Various benzoxazines can be conveniently synthesized in this reaction system. In addition, we carried out a series of mechanistic studies and optical experiments.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research