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Ligand‐Free FeCl 2 ‐Catalyzed α‐Alkylation of Ketones with Alcohols
Author(s) -
Ibrahim Jessica Juweriah,
Reddy C. Bal,
Zhang Shaochun,
Yang Yong
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900438
Subject(s) - chemistry , alkylation , catalysis , primary (astronomy) , ligand (biochemistry) , organic chemistry , ketone , combinatorial chemistry , receptor , biochemistry , physics , astronomy
In this study, we present a facile, cost‐effective and expedient hydrogen‐borrowing strategy to perform α‐alkylation of ketones with primary alcohols using FeCl 2 as the catalyst. A set of both ketones and alcohols could be efficiently alkylated to produce their corresponding ketones in good to high yields.