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Visible‐Light‐Induced Trifluoromethylation of Quinoxalin‐2(1 H )‐Ones under Photocatalyst‐Free Conditions
Author(s) -
Wang Jiayang,
Sun Bin,
Zhang Liang,
Xu Tengwei,
Xie Yuanyuan,
Jin Can
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900414
Subject(s) - trifluoromethylation , chemistry , photocatalysis , photochemistry , visible spectrum , yield (engineering) , electron transfer , irradiation , energy transfer , organic chemistry , catalysis , optoelectronics , trifluoromethyl , alkyl , physics , materials science , nuclear physics , molecular physics , metallurgy
C−H trifluoromethylation of quinoxalin‐2(1 H )‐ones with commercially available sodium trifluoromethanesulfinate (CF 3 SO 2 Na) under visible light irradiation without any external photocatalyst has been developed, providing a variety of 3‐trifluoromethylquinoxalin‐2(1 H )‐ones in moderate to excellent yield. Mechanistic studies have shown that 1 O 2 coexists with O 2 .− through the energy transfer and single‐electron transfer processes during the photoredox reaction.