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Pivalic Acid‐Assisted Rh(III)‐Catalyzed C−H Functionalization of 2‐Arylpyridine Derivatives Using Arylsilanes
Author(s) -
Ghaderi Arash,
Iwasaki Takanori,
Kambe Nobuaki
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900362
Subject(s) - chemistry , pivalic acid , catalysis , reagent , surface modification , activator (genetics) , oxidative coupling of methane , combinatorial chemistry , organic chemistry , biochemistry , gene
We report herein a Rh(III)‐catalyzed oxidative coupling reaction of 2‐phenylpyridine derivatives with arylsilane reagents. In this reaction, AgF plays important roles as both oxidant and C−Si bond activator. Addition of the catalytic amount of pivalic acid was found to be the key to achieve high yields of the desired products in short reaction times.