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α,β‐Unsaturated Aldehydes as C‐Building Blocks in the Synthesis of Pyridines, 1,4‐Dihydropyridines and 1,2‐Dihydropyridines
Author(s) -
Vchislo N. V.
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900275
Subject(s) - chemistry , organic chemistry , combinatorial chemistry
N ‐heterocycles are ubiquitous structural units in a variety of biologically active compounds, pharmaceutical preparations, and natural complex molecules. Thousands of original scientific papers are published annually on various aspects of the formation of nitrogenous heterocycles and the study of their chemical and biological properties. Among them, the synthesis of pyridines and their dihydrogenated derivatives attracts the attention of chemists, which develop synthetic techniques, including those ones based on α,β‐unsaturated aldehydes. The minireview summarizes and highlights the recent advancements in the construction of pyridines, 1,2‐dihydropyridines, and 1,4‐dihydropyridines from transformations of 2‐alkenals, covering the publications of the last five years.

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