Premium
Rhodium‐Catalyzed [5+1]‐Cycloaddition Reactions to Spiro‐Benzo[ e ][1,3]Oxazineindoline Imines
Author(s) -
Han Cuifen,
Wu Wenjin,
Chen Zhiyuan,
Pu Shouzhi
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900274
Subject(s) - chemistry , cycloaddition , imine , rhodium , isoxazole , catalysis , medicinal chemistry , organic chemistry
A Rh‐catalyzed [5+1] cycloaddition reaction for the synthesis of spirocyclicindoline imine from 3‐diazoindolin‐2‐imine with benzo[ d ]isoxazole is reported. The reaction proceeds under gentle catalytic conditions, thus giving the expected spiro[benzo[ e ][1,3]oxazine‐2,3′‐indolin]‐2‐imines with good functional‐group tolerance.