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Biosynthetic Relationships and Total Syntheses of Naturally Occurring Benzo[ c ]Phenanthridine Alkaloids
Author(s) -
Bisai Vishnumaya,
Saina Shaheeda M. K.,
Gupta Aditi,
Bisai Alakesh
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900244
Subject(s) - phenanthridine , chemistry , alkaloid , stereochemistry , total synthesis
Benzo[ c ]phenanthridine alkaloids sharing a tetracyclic structural motif, are an important class of nitrogen‐containing small molecules and are used for the treatment of a number of diseases. This review presents a comprehensive survey of the occurrence, chemistry, biochemistry, and biological activity of benzophenanthridine alkaloids. Synthetic approaches to a number of benzo[ c ]phenanthridine are disclosed in this Minireview.