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Iron‐Catalyzed Ortho ‐Selective C−H Alkylation of Aromatic Ketones with N ‐Alkenylindoles and Partial Indolylation via 1,4‐Iron Migration
Author(s) -
Kimura Naoki,
Kochi Takuya,
Kakiuchi Fumitoshi
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900209
Subject(s) - chemistry , alkylation , catalysis , medicinal chemistry , organic chemistry
An ortho ‐selective C−H alkylation of aromatic ketones with N ‐alkenylindoles proceeded in the presence of just a Fe(PMe 3 ) 4 catalyst. In addition, C−H indolylation products, which are considered to be formed via 1,4‐iron migration, were also observed as minor products.