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Efficient Access to 2‐Pyrones via Carbene‐Catalyzed Oxidative [3+3] Reactions between Enals and Nitrogen Ylides
Author(s) -
Zheng Pengcheng,
Li Chengcheng,
Mou Chengli,
Pan Dingwu,
Wu Shuquan,
Xue Wei,
Jin Zhichao,
Chi Yonggui Robin
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900153
Subject(s) - chemistry , carbene , pyridinium , catalysis , acetophenone , nitrogen , cycloaddition , organocatalysis , bromide , oxidative phosphorylation , combinatorial chemistry , organic chemistry , enantioselective synthesis , biochemistry
Abstract Pyrones are important structural units in natural products and synthetic functional molecules. Here, we report a carbene‐catalyzed oxidative [3+3] cycloaddition reaction between enals and nitrogen ylides for quick access to 2‐pyrones. Inexpensive and easily prepared 2′‐pyridinium acetophenone bromide salts are used as precursors of pyridinium ylides to react with enals in our catalytic reactions.