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Acylation of Arylamines with Triethylamine Derivatives in Combination with tert ‐Butyl Hydroperoxide
Author(s) -
Chen Cui,
Liu Weibing.,
Liu Bifu.,
Zhou Peng,
Tan Hua
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201900119
Subject(s) - chemistry , triethylamine , acylation , amine gas treating , alkyl , acyl group , organic chemistry , cleavage (geology) , medicinal chemistry , catalysis , geotechnical engineering , fracture (geology) , engineering
N‐acylation of arylamines with di‐ and trialkyl amines has been reported. This approach provides a general synthesis of aromatic amides by an alkyl transfer through cleavage of the C−N bond, and acts as a model for N‐dealkylations and N‐acylations. Additionally, the synthesis is a promising method towards amidation reactions, wherein di‐ and trialkyl amine derivatives are employed as sources of acyl carbon atoms and tert ‐butyl hydroperoxide is employed as the oxygen source of the acyl group.