Palladium‐Catalyzed C( sp  2 )−H Activation for the Formation of C−N Bonds: Rapid Access to Benzimidazoquinazolines | Zendy

Guo Xiaolong | Zendy; Hu Jing | Zendy; Zhang Mengmeng | Zendy; Wang Luyao | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Palladium‐Catalyzed C( sp 2 )−H Activation for the Formation of C−N Bonds: Rapid Access to Benzimidazoquinazolines

Author(s) -

Guo Xiaolong,

Hu Jing,

Zhang Mengmeng,

Wang Luyao

Publication year - 2019

Publication title -

asian journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 44

eISSN - 2193-5815

pISSN - 2193-5807

DOI - 10.1002/ajoc.201800710

Subject(s) - chemistry , catalysis , palladium , combinatorial chemistry , azole , medicinal chemistry , stereochemistry , organic chemistry , antifungal , medicine , dermatology

A convenient and effective method for Pd‐catalyzed cross‐dehydrogenative C( sp 2 )−H/N−H couplings to synthesize fused N‐heterocyclic benzimidazoquinazoline derivatives was developed. The reaction employs Pd(OAc) 2 as the catalyst and Cu(OAc) 2 or O 2 (from the air) as the terminal oxidant. The strategy uses simple and easily accessible substrates. This method provides a route to azole‐fused heterocycles.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research