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The Nitromethylation of 1,3‐Diarylpropenes Mediated by DDQ: N,N ‐Dimethyl‐2‐Nitroethyleneamine as a Nitromethane Equivalent
Author(s) -
Deng Zhiteng,
Cheng Dongping,
Xu Xiaoliang,
Yan Jizhong
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800672
Subject(s) - nitromethane , chemistry , medicinal chemistry , organic chemistry
Abstract The nitromethylation of 1,3‐diarylpropenes via 2,3‐dichloro‐5,6‐dicyano‐1,4‐benzoquinone (DDQ) mediated C−H oxidative activation is reported, in which N , N ‐dimethyl‐2‐nitroethyleneamine is used as a nitromethane equivalent. The precedent method for the synthesis of 1,3‐diaryl‐2‐propenylnitromethanes is safe and easy to work‐up.