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A Highly Efficient Copper‐Catalyzed C(sp 2 )−H Alkoxylation of the Benzamide Enabled by A Bidendate Directing Group
Author(s) -
Hu Yu,
Wang Min,
Li Pinhua,
Li Hongji,
Wang Lei
Publication year - 2019
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800664
Subject(s) - benzamide , chemistry , alkyl , catalysis , regioselectivity , aryl , copper , medicinal chemistry , group (periodic table) , organic chemistry , combinatorial chemistry , stereochemistry
We herein describle an efficient Cu(I)‐catalyzed direct alkoxylation of N ‐(8‐quinolinyl)benzamide with alcohols under air that afforded a number of alkyl aryl ethers in high regioselectivity and good isolated yields.
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