Cobalt‐Catalyzed Reductive Coupling of Alkynes and Acrylates Bearing a Leaving Group: Construction of Cyclobutene Rings | Zendy

Fujihara Tetsuaki | Zendy; Kukita Susumu | Zendy; Yagi Yuki | Zendy; Kirihara Maho | Zendy; Nogi Keisuke | Zendy; Tsuji Yasushi | Zendy

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Cobalt‐Catalyzed Reductive Coupling of Alkynes and Acrylates Bearing a Leaving Group: Construction of Cyclobutene Rings

Author(s) -

Fujihara Tetsuaki,

Kukita Susumu,

Yagi Yuki,

Kirihara Maho,

Nogi Keisuke,

Tsuji Yasushi

Publication year - 2018

Publication title -

asian journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 44

eISSN - 2193-5815

pISSN - 2193-5807

DOI - 10.1002/ajoc.201800561

Subject(s) - cyclobutene , chemistry , catalysis , cobalt , lewis acids and bases , acetonitrile , medicinal chemistry , group (periodic table) , bearing (navigation) , polymer chemistry , photochemistry , organic chemistry , ring (chemistry) , cartography , geography

This study reports a cobalt‐catalyzed synthesis of cyclobutenes using alkynes and acrylates bearing a leaving group at the α position. The cyclobutene formation was facilitated by an appropriate proton source. In the presence of a Lewis acid, acetonitrile participated in the reaction, affording the corresponding functionalized cyclobutenes.

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