Chiral Bifunctional Ferrocenylphosphine‐Catalyzed Enantioselective Allylic Alkylation of Morita−Baylis−Hillman Carbonates with Pyrazolin‐5‐ones | Zendy

Luo Wenjun | Zendy; Song Dingguo | Zendy; Fang Lu | Zendy; Nian Sanfei | Zendy; Hou Huacui | Zendy; Ling Fei | Zendy; Zhong Weihui | Zendy

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Chiral Bifunctional Ferrocenylphosphine‐Catalyzed Enantioselective Allylic Alkylation of Morita−Baylis−Hillman Carbonates with Pyrazolin‐5‐ones

Author(s) -

Luo Wenjun,

Song Dingguo,

Fang Lu,

Nian Sanfei,

Hou Huacui,

Ling Fei,

Zhong Weihui

Publication year - 2018

Publication title -

asian journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 44

eISSN - 2193-5815

pISSN - 2193-5807

DOI - 10.1002/ajoc.201800547

Subject(s) - chemistry , bifunctional , enantioselective synthesis , tsuji–trost reaction , allylic rearrangement , catalysis , alkylation , organic chemistry

A chiral bifunctional ferrocenylphosphine catalyzed asymmetric allylic alkylation of Morita−Baylis−Hillman (MBH) carbonates with pyrazolin‐5‐ones was developed. The reaction afforded the desired pyrazolone derivatives in moderate to good yields (up to 80%), and with high enantioselectivities (up to 98% ee ).

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