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Ultrasound‐Assisted Multicomponent Reactions, Organometallic and Organochalcogen Chemistry
Author(s) -
Penteado Filipe,
Monti Bonifacio,
Sancineto Luca,
Perin Gelson,
Jacob Raquel G.,
Santi Claudio,
Lenardão Eder J.
Publication year - 2018
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800477
Subject(s) - chemistry , organic synthesis , organic reaction , organometallic chemistry , green chemistry , microwave chemistry , organic chemistry , nanotechnology , catalysis , group 2 organometallic chemistry , combinatorial chemistry , biochemical engineering , microwave irradiation , molecule , reaction mechanism , materials science , engineering
In the last two decades, the search for sustainability in chemical reactions has attached a lot of attention. In this focus review, the use of ultrasound (US) as an alternative energy source in organic synthesis is presented. The improvement of the performance of chemical reactions due to the cavitation effect has been previously studied and described. The use of US guarantees often higher yields than other green methodologies, as microwave or ball milling. The impressive positive effect of US in organic synthesis are demonstrated in this review mainly in organometallic and multi‐component reactions (MCRs), aimed to prepare bioactive compounds. A particular attention is dedicated to the US‐assisted synthesis of valuable organochalcogen compounds with pharmacological activity.