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Rh(III)‐Catalyzed C‐H Amination of Azobenzenes with Anthranils
Author(s) -
Fu Ting,
Yang Jun,
Sun Huihui,
Zhang Chichen,
Xiang Haifeng,
Zhou Xiangge
Publication year - 2018
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800386
Subject(s) - chemistry , amination , acridine , regioselectivity , catalysis , indole test , aryl , organic chemistry , combinatorial chemistry , medicinal chemistry , alkyl
An efficient Rh(III)‐catalyzed C−H amination of azobenzenes with anthranils was developed. A range of azobenzenes were aminated under mild conditions in high yields (up to 92%) with good regioselectivity and atomic economy. The formed ortho ‐aminocarbonyl skeleton could be converted to a series of biologically interesting heterocyclic compounds including a dibenzodiazepine, an acridine and an N ‐aryl indole.
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